Identifiers
NAME:ORP1L*:RAB7*:RILP
References
DENDRITIC_CELL
PMID:11696325, PMID:21112200
The Rab7???RILP complex interacts with a second EFFECTOR_ACTIVATION protein???OSBP???related protein 1L (ORP1L)???to form a tripartite complex on lysosomal membranes.
This complex regulate transport vesicules with of MHC class II complex along microtubes.
in_re28( Innate Immunity ):
PMID:21458045
MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an EFFECTOR_ACTIVATION protein ARF7EP. This complex controls movement of MHC-II vesicles along the actin cytoskeleton in human dendritic cells (DCs).