Protein ARL14EP
Identifiers
HUGO:ARL14EP
References
DENDRITIC_CELL
PMID:21458045
MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an EFFECTOR_ACTIVATION protein ARF7EP. This complex controls movement of MHC-II vesicles along the actin cytoskeleton in human dendritic cells (DCs).
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- ARL14EP@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- ARL14:ARL14EP:GTP:MYO1E@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- ARL14:GTP@INNATE_IMMUNE_CELL_Cytosol
+ ARL14EP@INNATE_IMMUNE_CELL_Cytosol
+ MYO1E@INNATE_IMMUNE_CELL_Cytosol
→
ARL14:ARL14EP:GTP:MYO1E@INNATE_IMMUNE_CELL_Cytosol
As Catalyser:- MHC_class_II*:Tumor_antigen_fragment@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane
→
MHC_class_II*:Tumor_antigen_fragment@INNATE_IMMUNE_CELL_Membrane