Protein cGAS* map

Identifiers
HUGO:TMEM173

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / DANGER_SIGNAL_PATHWAYS  map

References
 DENDRITIC_CELL  map
CASCADE:STING
PMID:24766893
Cytosolic DNA induces type I IFNs through the endoplasmic reticulum membrane protein STING, which subsequently activates the transcription factors NF-??B and IRF3 through the kinases IKK and TBK1, respectively

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. cGAS*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. TUMOR_DNA:​cGAS*@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. gTUMOR_DNA@INNATE_IMMUNE_CELL_Cytosol map + cGAS*@INNATE_IMMUNE_CELL_Cytosol map → map TUMOR_DNA:​cGAS*@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. ATP@INNATE_IMMUNE_CELL_Cytosol map → map cGAMP@INNATE_IMMUNE_CELL_Cytosol map