Protein CD36 map

Identifiers
HUGO:CD36 HGNC:1663
HUGO:CD36

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map
 Innate Immunity  map  / DANGER_SIGNAL_PATHWAYS  map

References
PMID:?2015-MOJCSR-02-00015 PMID:21378271
 DENDRITIC_CELL  map
 MACROPHAGE  map
CASCADE:IL13
CASCADE:IL4
CASCADE:THBS1
CASCADE:CD36
PMID:9295024, PMID:9763615
Dendritic cells phagocytose apoptotic cells via alphavbeta5, alphavbeta3, and CD36.
Cross-present Antigens to Cytotoxic T Lymphocytes.
The interaction between apoptotic bodies and dendritic cells elicits a rise in intracellular free calcium concentration ([Ca2+]i) which is essential for the process of engulfment.
PMID:17101731
Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells.
PMID:14568985
The exogenous and endogenous TSP produced during early DC activation negatively regulates IL-12, TNF-??, and IL-10 release through its interactions with CD47 and probably CD36

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD36@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD36:​oxPS@INNATE_IMMUNE_CELL_Membrane map
  2. CD36:​THBS1@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. THBS1@default map + CD36@INNATE_IMMUNE_CELL_Membrane map → map CD36:​THBS1@INNATE_IMMUNE_CELL_Membrane map
  2. rCD36@INNATE_IMMUNE_CELL_Cytosol map → map CD36@INNATE_IMMUNE_CELL_Membrane map
  3. oxPS@default map + CD36@INNATE_IMMUNE_CELL_Membrane map → map CD36:​oxPS@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. Tumor_antigen@TUMOR_CELL_AS_EFFECTOR map → map Tumor_antigen@PHAGOSOME/ENDOSOME/LYSOSOME_Membrane map