Complex CCL19:CCR7
Complex composition:
- CCR7
- CCL19
CCL19:CCR7@INNATE_IMMUNE_CELL_Membrane
Identifiers
NAME:CCL19:CCR7
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ RECRUITMENT_OF_IMMUNE_CELLS
References
DENDRITIC_CELL
CASCADE:CCR7
PMID:11698286
IFNA induces mRNA expression both CCR7 and it's ligand CCL19 in Dcs and induces Dcs migration
PMID:19759904
Jak3 is important for DC maturation, migration and function, through a CCR7-mediated signalling pathway.
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
- CCL19:CCR7@INNATE_IMMUNE_CELL_Membrane
Participates in reactions:
As Reactant or Product:- CCL19@default
+ CCR7@INNATE_IMMUNE_CELL_Membrane
→
CCL19:CCR7@INNATE_IMMUNE_CELL_Membrane
As Catalyser:- JAK3@INNATE_IMMUNE_CELL_Cytosol
→
JAK3@INNATE_IMMUNE_CELL_Cytosol