RNA MYC map

Identifiers
v-myc myelocytomatosis viral oncogene homolog
HUGO:MYC, HGNC:7553, ENTREZ:4609, GENECARDS:GC08P128748
v-myc myelocytomatosis viral oncogene homolog (avian)
HUGO:MYC HGNC:7553 ENTREZ:4609 UNIPROT:P01106
HUGO:MYC
"v-myc avian myelocytomatosis viral oncogene homolog"
HUGO:MYC HGNC:7553 ENTREZ:4609 UNIPROT:P01106 GENECARDS:MYC REACTOME:59773 KEGG:4609 ATLASONC:MYCID27 WIKI:MYC

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / METABOLIC  map
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / SENESCENCE  map
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
 Regulated Cell Death  map  / APOPTOSIS  map
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / MITOCHONDRIAL_GENES  map
 Regulated Cell Death  map  / MOMP_REGULATION  map
 Regulated Cell Death  map  / RCD_GENES  map
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_CANONICAL  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:25002027
We found significantly reduced levels of c-Myc in p62 KO fibroblasts as well as in WT fibroblasts in which p62 has been knocked down by shRNA
PMID:22067385
c-MYC expression is assosiated with M2 type of macrophages.
IL4 induces MYC expression in macrophages. MYC directly regulates some genes associated with alternative activation, including SCARB1, ALOX15, and MRC1, whereas others, including CD209, are indirectly regulated by c-MYC. c-MYC up-regulates the IL-4 signaling mediators signal transducer and activator of transcription-6 and peroxisome proliferator-activated receptor??, is also expressed in tumor-associated macrophages, and its inhibition blocks the expression of protumoral genes including VEGF, MMP9, HIF-1A, and TGFB.
PMID:20581311
STAT3 as an essential mediator of emergency granulopoiesis by its regulation of transcription factors that direct G-CSF-responsive myeloid progenitor expansion.
STAT3 directly controls G-CSF-dependent expression of CCAAT-enhancer-binding protein ?? (C/EBP??), a crucial factor in the emergency granulopoiesis response. Moreover, STAT3 and C/EBP?? coregulate c-Myc through interactions with the c-myc promoter that control the duration of C/EBP?? occupancy during demand-driven granulopoiesis.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rMYC@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMYC@INNATE_IMMUNE_CELL_Cytosol map → map rMYC@INNATE_IMMUNE_CELL_Cytosol map
    2. rMYC@INNATE_IMMUNE_CELL_Cytosol map → map MYC@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: