Identifiers
nerve growth factor
HUGO:NGF hgnc_id:HGNC:7808 HGNC:7808 ENTREZ:4803 UNIPROT:P01138
nerve growth factor (beta polypeptide)
HUGO:NGF HGNC:7808 ENTREZ:4803 UNIPROT:P01138
HUGO:NGF
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
Cancer Associated Fibroblasts / GROWTH_FACTORS_PRODUCTION
HMC:RESISTING_CELL_DEATH
Regulated Cell Death / DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death / DEPENDANCE_RECEPTORS
Innate Immunity / TUMOR_GROWTH
References
PMID:25071162
PMID:22465479
MAST_CELL
PMID:15099563
Mast cells produce heparin, interleukin-8 (IL-8) and vascular
endothelial cell growth factor (VEGF), which induce
neovascularization, histamine, which is an immunosuppressant,
mitogenic factors, such as platelet-derived
growth factor (PDGF), nerve GF (NGF), stem-cell factor
(SCF), and proteases, which disrupt the surrounding
matrix and facilitate metastases.
PMID:17764704
NGF is angiogenic factor