Complex Ca2+:Calmodulin*
Complex composition:
- Calmodulin*
- Ca2+
Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
Identifiers
NAME:Ca2+:Calmodulin*
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ IMMUNOSTIMULATORY_CORE_PATHWAYS
References
NATURAL_KILLER
CASCADE:Fc_gamma_RIII
PMID:10089876, PMID:7650486, PMID:9973469
??Ca('2+)??activates Calmodulin 2 (??Calmodulin??)/ Protein phosphatase 3 (Calcineurin??) signal. Activated??Calcineurin??dephosphorylates Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 2 (??NF-AT1(NFATC2)??).??
This signaling is activated downstream of CD16 in NK cells
Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- Ca2+@INNATE_IMMUNE_CELL_Cytosol
+ Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
→
Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
- Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
+ CNA*:CNB*@INNATE_IMMUNE_CELL_Cytosol
→
CNA*:CNB*:Ca2+:Calmodulin*@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: