Antisense RNA MIR27A* map

Identifiers
HUGO:MIR27A

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map

References
 NATURAL_KILLER  map
CASCADE:IL15
PMID:21960590
IL15 induces mir27A* expression in activated NK cells.
Human miR-27a* specifically bound to the 3' untranslated regions of Prf1 and GzmB, down-regulating expression in both resting and activated NK cells.
Tumor growth was inhibited by mNK cells, the inhibitory effect of mNK cells was significantly decreased by miR-27a* overexpression. In contrast, transfection of mNK cells with miR-27a* inhibitor resulted in enhanced antitumor activity

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR27A*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. GZMB:​MIR27A*@INNATE_IMMUNE_CELL_Cytosol map
  2. MIR27A*:​PRF1@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. MIR27A*:​PRF1@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  2. GZMB:​MIR27A*@INNATE_IMMUNE_CELL_Cytosol map → map degraded
  3. arMIR27A*@INNATE_IMMUNE_CELL_Cytosol map + rGZMB@INNATE_IMMUNE_CELL_Cytosol map → map GZMB:​MIR27A*@INNATE_IMMUNE_CELL_Cytosol map
  4. arMIR27A*@INNATE_IMMUNE_CELL_Cytosol map + rPRF1@INNATE_IMMUNE_CELL_Cytosol map → map MIR27A*:​PRF1@INNATE_IMMUNE_CELL_Cytosol map
  5. gMIR27A*@INNATE_IMMUNE_CELL_Cytosol map → map arMIR27A*@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser: