Protein FLT3 map

Identifiers
HUGO:FLT3

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map

References
CASCADE:FLT3LG
PMID:15253381
It was found that
the following signal transduction molecules were all
activated by the stimulated FLT3 receptor: phospholipase g-1,
RAS GTPase-activating protein GAP, p85 subunit of
phosphatidylinositol 3-kinase (PI3
K), SH2-containing
sequence proteins (SHCS), SH2-domain-containing inositol phosphatase (SHIP), GRB2, VAV, FYN and SRC. Of
these, various molecules were shown to directly physically
asssociate with the FLT3 cytoplasmic domain. These
proteins are involved in different signal transduction
pathways, including the RAS-RAF-MEK-ERK pathway

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. FLT3@INNATE_IMMUNE_CELL_Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. FLT3@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. FLT3:​FLT3LG@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. FLT3LG@default map + FLT3@INNATE_IMMUNE_CELL_Membrane map → map FLT3:​FLT3LG@INNATE_IMMUNE_CELL_Membrane map
  2. rFLT3@INNATE_IMMUNE_CELL_Cytosol map → map FLT3@INNATE_IMMUNE_CELL_Cytosol map
  3. FLT3@INNATE_IMMUNE_CELL_Cytosol map → map FLT3@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. STAT3@INNATE_IMMUNE_CELL_Cytosol map → map STAT3|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map