Protein IL1RAP map

Identifiers
interleukin 1 receptor accessory protein
HUGO:IL1RAP hgnc_id:HGNC:5995 HGNC:5995 ENTREZ:3556 UNIPROT:Q9NPH3
HUGO:IL1RAP

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / INFLAMMATORY_SIGNALING_PATHWAYS  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / RECRUITMENT_OF_IMMUNE_CELLS  map

References
CASCADE:IL1
PMID:18977329
IL-1?? activates MDSC in vitro and in vivo through an IL-1RI/NF-??B pathway.
 MDSC  map

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. IL1R1:​IL1RAP@INNATE_IMMUNE_CELL_Membrane map
  2. IL1R1:​IL1RAP:​trILB1@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. IL1R1:​IL1RAP:​trILB1@INNATE_IMMUNE_CELL_Membrane map → map RECRUITMENT_OF_IMMUNE_CELLS@INNATE_IMMUNE_CELL_Cytosol map
  2. trILB1@default map + IL1R1:​IL1RAP@INNATE_IMMUNE_CELL_Membrane map → map IL1R1:​IL1RAP:​trILB1@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. NFkB*@INNATE_IMMUNE_CELL_Cytosol map → map NFkB*@INNATE_IMMUNE_CELL_Cytosol map