Reaction state_transition in_re1281 map

CREB1@INNATE_IMMUNE_CELL_Cytosol map CREB1|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map

Reaction regulators:
Catalysis
  1. p38*|​pho|​active@INNATE_IMMUNE_CELL_Cytosol map
Inhibition
  1. GSK3_beta_*@INNATE_IMMUNE_CELL_Cytosol map


References
PMID:16713974
TLR activation of CREB by phosphorylation of serine-133 is dependent on p38.
GSK3B inhibits IL10 expression downstream of IFNG, probably via GREB1 inhibition.
PMID:16007092
GSK3B inhibits CREB1 interaction CBP and inhibits CREB1 dependent IL10 expression.