Reaction state_transition in_re1154
GSK3_beta_*@INNATE_IMMUNE_CELL_Cytosol
→ GSK3_beta_*|pho@INNATE_IMMUNE_CELL_Cytosol
Reaction regulators:
- Catalysis
- AKT*|pho@INNATE_IMMUNE_CELL_Cytosol
References
PMID:16713974
AKT kinases phosphorylate GSK3 proteins and inhibit its activity downstream of TLR signaling.
IFNG prevents this inactivation.