RNA HIF2A* map

Identifiers
HUGO:EPAS1

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map

References
PMID:20194441
HIF2a expression is assosiated with M2 phenotype.
PMID:11888900, PMID:20644254
HIF2A induces tumor growth and angiogenesis.
PMID:16127144
HIF-1A and HIF-2A are up-regulated by human macrophages exposed to hypoxia??in vitro??and by TAMs in hypoxic/necrotic areas of human tumors
PMID:20644254
HIF2a induces macrophage migration via upregulation of CXCR4, FN1 expression and upregulation of M-CSFR protein level.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. rHIF2A*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gHIF2A*@INNATE_IMMUNE_CELL_Cytosol map → map rHIF2A*@INNATE_IMMUNE_CELL_Cytosol map
    2. rHIF2A*@INNATE_IMMUNE_CELL_Cytosol map → map HIF2A*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: