Identifiers
HUGO:RELB
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / IMMUNOSTIMULATORY_CORE_PATHWAYS
References
DENDRITIC_CELL
CASCADE:VEGFA
PMID:9570538
VEGF inhibits TNF-?? inducible activation of NF-??B in HPC, resulting in inhibition of DC differentiation
The presence of VEGF significantly decreased the specific DNA binding of NF-kappa B as early as 30 min after induction with TNF-alpha. This was followed on days 7 to 10 by decreases in the mRNA for RelB and c-Rel, two subunits of NF-kappa B.