Reaction transcription in_re719
gSOCS1@INNATE_IMMUNE_CELL_Cytosol
→ rSOCS1@INNATE_IMMUNE_CELL_Cytosol
Reaction regulators:
- Catalysis
- IRF1@INNATE_IMMUNE_CELL_Cytosol
- STAT1|pho|active@INNATE_IMMUNE_CELL_Cytosol
- IL4@default
- IL13@default
References
PMID:12433365, PMID:10485906
INFG induces SOCS1 expression in macrophages.
PMID:10820262
Probably IFNG induces SOCS1 expressiov via IRF1 upregulation downstream of STAT1
PMID:21097505
IL13 induces SOCS1 expression.