Reaction transcription in_re568
gCCL3@INNATE_IMMUNE_CELL_Cytosol
→ rCCL3@INNATE_IMMUNE_CELL_Cytosol
Reaction regulators:
- Inhibition
- HDAC3:NCOR1:PPARG:SUMO*:TBL1X:TBL1XR1@INNATE_IMMUNE_CELL_Cytosol
- TGFB*:TGFBR1:TGFBR2@INNATE_IMMUNE_CELL_Membrane
References
PMID:16127449
PPARG sumoilated by PIAS1/UbC9 prevents dissociation of the NCoR???HDAC3 complex fro promoters and transrepresses expression NOS2, Ccl3, Ccl7, Cxcl10