References
PMID:21115385, PMID:10433356
IL10??? ???acts via IL10??? ???receptor.
IL10??? ???first binds to IL10RA
The IL10/IL10R1A ???interaction changes the cytokine
conformation allowing the association of
the IL10/IL10RA ???complex with IL10RB.
PMID:???15833879
???Anti IL-10 receptor???specific antibody
switched TAMs from an M2 to an M1
macrophage???like phenotype.