Protein CSF1R map

Identifiers
HUGO:CSF1R

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
PMID:10705574
CSF1 acts via CSF1R
PMID:20644254
HIF2a induces macrophage migration via upregulation of CXCR4, FN1 expression and upregulation of CSF1R protein level.
PMID:11306493
IL4 signaling prevents CSF2RA(CD116) lost on DC surface in tumor microenviroment.
and blocks gp130 and CSF1R (CD115)surface expression.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CSF1R@INNATE_IMMUNE_CELL_Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CSF1R@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CSF1:​CSF1R@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. CSF1:​CSF1R@INNATE_IMMUNE_CELL_Membrane map → map IMMUNE_SUPRESSION@default map
  2. rCSF1R@INNATE_IMMUNE_CELL_Cytosol map → map CSF1R@INNATE_IMMUNE_CELL_Cytosol map
  3. CSF1R@INNATE_IMMUNE_CELL_Cytosol map → map CSF1R@INNATE_IMMUNE_CELL_Membrane map
  4. CSF1@default map + CSF1R@INNATE_IMMUNE_CELL_Membrane map → map CSF1:​CSF1R@INNATE_IMMUNE_CELL_Membrane map
As Catalyser: