Identifiers
HUGO:ITGAX
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / MARKERS_DC
Innate Immunity / MARKERS_NEUTROPHIL
Innate Immunity / INTEGRINS
Innate Immunity / DANGER_SIGNAL_PATHWAYS
References
DENDRITIC_CELL
MACROPHAGE
CASCADE:MIF
CASCADE:CR4
CASCADE:FLT3LG
CASCADE:IFNAB
PMID:15573129
CD11c is a maker of myeloid DCs.
PMID:8920882
FLT3 ligand upregulates surface expression of CD11c in DCs.
PMID:23390297
MIF inhitits expression of M1 markers such as TNF, IL12p40, COX2, INOS, IRF-5, MHC-II, CD11c, CD80, CD86 and MIF induces expression of M2 markers as IL10, stabilin-1, MRC-1, CD206, CD23
PMID:??11207245
I IFN receptor signaling regulates antigen cross-presentation to CD8(+) T cells. (), probably via upregulation of CD80, CD86, CD40, CD83 and MHC class II and CD11c,
PMID:17513775
Probably via STAT1(demondrtated for CD40 and CD11c PMID:14764699, and for CD40, CD80, CD86, and MHC II?? )