Phenotype Actin_polymerization
Actin_polymerization@INNATE_IMMUNE_CELL_Cytosol
References
PMID:14612578
In NK cells actin and microtubule polymerization are required for cytotoxic function.
PMID:16887996
Vav1 is required for actin accumulation at the NK-target contact site in response to NKG2D-DAP10 signals,
probably via RHOA pathway.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- Actin_polymerization@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- Actin_polymerization@INNATE_IMMUNE_CELL_Cytosol
→
Granules_exocytosis@INNATE_IMMUNE_CELL_Membrane
- Actin cytoskeletal*|hm2|active@INNATE_IMMUNE_CELL_Cytosol
→
Actin_polymerization@INNATE_IMMUNE_CELL_Cytosol
- Actin_polymerization@INNATE_IMMUNE_CELL_Cytosol
→
EXOCYTOSIS_AND_PHAGOCYTOSIS@INNATE_IMMUNE_CELL_Membrane
As Catalyser: