Protein OSM map

Identifiers
oncostatin M
HUGO:OSM hgnc_id:HGNC:8506 HGNC:8506 ENTREZ:5008 UNIPROT:P13725
HUGO:OSM

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / INFLAMMATORY_SIGNALING_PATHWAYS  map
 Innate Immunity  map  / TUMOR_GROWTH  map

References
CASCADE:IL6
PMID:21840487
Jak 1 regulates Actomyosin Contractility in CAFs downstream of GP130-IL6ST IL6 and oncostatin M (OSM) and via STAT3
 NEUTROPHIL  map
PMID:16204061
Upon contact with breast carcinoma cell lines in vitro neutrophils secrete oncostatin M. This pleiotropic cytokine induces breast cancer cells to secrete VEGF and thus promote angiogenesis

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. OSM@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. OSM@INNATE_IMMUNE_CELL_Cytosol map → map ANGIOGENESIS@default map
    As Catalyser: