Identifiers
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
HUGO:PIP5K1A HGNC:8994 ENTREZ:8394 UNIPROT:Q99755
HUGO:PIP5K1A
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / CYTOSKELETON_POLARITY
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / IMMUNOSTIMULATORY_CORE_PATHWAYS
References
DENDRITIC_CELL
NATURAL_KILLER
CASCADE:Fc_gamma_RIII
PMID:21458045
PSD4 is selectively expressed in the immune system and promotes GTP loading of ARL14/ARF7.
Probably downstream of PIP5K1A.
PMID:15817676
Arf6 couples CD16 to the lipid-modifying enzymes phosphatidylinositol4phosphate 5-kinase type I alpha (PI5KI??) and phospholipase D (PLD) that are involved in the control of granule secretion