Identifiers
NAME:PPARG:STAT6
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity / IMMUNOSUPPPRESSIVE_CORE_PATHWAYS
References
PMID:17681149
STAT6, by interacting with PPAR??, facilitates and is required for efficient endogenous PPAR?? binding.
STAT6 and PPAR?? together upregulate CD36 transcription.
in_re1111( Innate Immunity ):
PMID:10432118
ALOX15 activation results in induction of CD36 expression downstream of IL4 and IL13 via PRARG
CD36 gene expression is directly controlled by 15-LO expression/activity in IL-13-driven monocytes/macrophages