Phenotype EAT_ME
EAT_ME@TUMOR_CELL_AS_INDUCTOR
References
PMID:22437871
The eat me signals are membrane-bound and serve as markers for phagocytes for recognizing and internalizing dying cells. These signals include phosphatidylserine, alterations in cell-surface charge, ??v??5 integrin and CD36. The eat me signals also include molecules such as milk fat globule-EGF factor 8 (MFG-E8; also known as lactadherin), which bridge the phosphatidylserine of apoptotic cells with the integrin ??v??3 of DCs
Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR
- EAT_ME@TUMOR_CELL_AS_INDUCTOR
Participates in complexes:
Participates in reactions:
As Reactant or Product:- DYING_TUMOR_CELL@TUMOR_CELL_AS_INDUCTOR
→
EAT_ME@TUMOR_CELL_AS_INDUCTOR
- EAT_ME@TUMOR_CELL_AS_INDUCTOR
→
MFGE8@TUMOR_CELL_AS_INDUCTOR_Membrane
- EAT_ME@TUMOR_CELL_AS_INDUCTOR
→
PtdSer@TUMOR_CELL_AS_INDUCTOR_Membrane
- EAT_ME@TUMOR_CELL_AS_INDUCTOR
→
CALR@default
As Catalyser: