Complex LGALS3:SLC3A2 map
Complex composition:

  1. SLC3A2 map
  2. LGALS3 map

LGALS3:​SLC3A2@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:LGALS3:SLC3A2

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
PMID:18250477
An IL-4-mediated LGALS3 (galectin-3) autocrine loop promotes alternative macrophage activation and is blocked by pharmacological inhibition of galectin-3 and its receptor SLC3A2 (CD98)
in_re163( Innate Immunity  map ):
PMID:16713974
TLR signaling activates and IFNG inhibits PI3K pathway
PMID:11907067, PMID:15536084
SYK kinaze directly interacts with PI3K(p85) and activates perforin ??granule movement and polarization via PI3K /RAC1/PAK1/MEK??/ERK pathway
PMID:10426994??
Phosphorylated DAP10 directly interacts with regulatory subunit (p85) of PI3K and activates downstream pathway.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. LGALS3:​SLC3A2@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. LGALS3@default map + SLC3A2@INNATE_IMMUNE_CELL_Membrane map → map LGALS3:​SLC3A2@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. PI3KR(p85)*@INNATE_IMMUNE_CELL_Cytosol map → map PI3KR(p85)*@INNATE_IMMUNE_CELL_Cytosol map