Phenotype MTOC_polarization
MTOC_polarization@INNATE_IMMUNE_CELL_Cytosol
References
PMID:16887996
Vav1 induces MTOC polarization at the NK-target contact site in response to NKG2D-DAP10 signals.
PMID:18287025
JNK induces assosiation of Paxilin with MTOC resulted in polarization of the MTOC and cytolytic granules, and finally exocytosis of cytolytic proteins downstream of NKG2D.
PMID:19689731
MTOC polarization is a significant step of exocytosis
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- MTOC_polarization@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- PXN:TUBGCP2:TUBGCP3:TUBGCP4:TUBGCP5:TUBGCP6:Tubulin-_alpha_*:Tubulin-_beta_*:Tubulin-_gamma_*@INNATE_IMMUNE_CELL_Cytosol
→
MTOC_polarization@INNATE_IMMUNE_CELL_Cytosol
- MTOC_polarization@INNATE_IMMUNE_CELL_Cytosol
→
Granules_exocytosis@INNATE_IMMUNE_CELL_Membrane
As Catalyser: