Protein PSD4 map

Identifiers
HUGO:PSD4

References
 DENDRITIC_CELL  map
PMID:21458045
PSD4 is selectively expressed in the immune system and promotes GTP loading of ARL14/ARF7.
Probably downstream of PIP5K1A.

PSD4@INNATE_IMMUNE_CELL_Cytosol

Identifiers
HUGO:STAT3

References
PMID:???21115385, PMID:7543512
???The binding of IL-10 to its receptor activates JAK1
Two tyrosines??? (???Tyr??? ???446??? ???and Tyr??? ???496???) ???of IL-10RA
are phosphorylated by the JAK1,??? ???to which
the transcription factor STAT3??? ???binds via its SH2??? ???domain
and in turn becomes itself phosphorylated.
PMID:10347215
Only JAK1/STAT3 pathway (but not TYK) plays role in
anti-inflammatory action of IL10 in macrophages.


Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. PSD4@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. PSD4@INNATE_IMMUNE_CELL_Cytosol map map PSD4@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser:
    1. ARL14:​GDP@INNATE_IMMUNE_CELL_Cytosol map + GTP@INNATE_IMMUNE_CELL_Cytosol map map ARL14:​GTP@INNATE_IMMUNE_CELL_Cytosol map + GDP@INNATE_IMMUNE_CELL_Cytosol map