Antisense RNA MIR200A map

Identifiers
microRNA 200a
HUGO:MIR200A, HGNC:31578, ENTREZ:406983, GENECARDS:GC01P001101
microRNA 200b
HUGO:MIR200A

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map
 Innate Immunity  map  / MIRNA_TF_IMMUNOSTIMULATORY  map

References
PMID:20592490
The MIR200 family comprises 5 members (MIR200A, B, C, MIR141 and MIR429).
These 5 members are clustered and expressed as 2 separate polycistronic pri-miRNA transcripts, miR200B-200A-429 and miR200C-141.
These 2 transcripts are located on human chromosomes 1 and 12, respectively.
 NATURAL_KILLER  map
CASCADE:IL12
PMID:22077060
The miRs-132, 212, and 200a were shown to be induced in human NK cells by IL-12 stimulation, which in turn target STAT4 mRNA, thereby providing a negative regulatory pathway for IL-12 signaling.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. arMIR200A@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. MIR200A:​STAT4@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. gMIR200A@INNATE_IMMUNE_CELL_Cytosol map → map arMIR200A@INNATE_IMMUNE_CELL_Cytosol map
  2. arMIR200A@INNATE_IMMUNE_CELL_Cytosol map + rSTAT4@INNATE_IMMUNE_CELL_Cytosol map → map MIR200A:​STAT4@INNATE_IMMUNE_CELL_Cytosol map
  3. MIR200A:​STAT4@INNATE_IMMUNE_CELL_Cytosol map → map degraded
As Catalyser: