Protein C5
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity
/ RECRUITMENT_OF_IMMUNE_CELLS
References
CASCADE:C5
MDSC
PMID:25050844, PMID:23028051
Cancer cells release anaphylatoxin C5a from C5 by serine protease to enhance invasiveness
PMID:18820683
C5a via C5AR regulates the accumulation and migration of MDSCs in tumor
Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR
- C5@TUMOR_CELL_AS_INDUCTOR
In compartment: default
- C5@default
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
- C5:C5AR*@INNATE_IMMUNE_CELL_Membrane
Participates in reactions:
As Reactant or Product:- C5@default
+ C5AR*@INNATE_IMMUNE_CELL_Membrane
→
C5:C5AR*@INNATE_IMMUNE_CELL_Membrane
- C5:C5AR*@INNATE_IMMUNE_CELL_Membrane
→
RECRUITMENT_OF_IMMUNE_CELLS@INNATE_IMMUNE_CELL_Cytosol
- C5@TUMOR_CELL_AS_INDUCTOR
→
C5@default
As Catalyser: