Protein GATA1
Identifiers
HUGO:GATA1
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity
/ MIRNA_TF_IMMUNOSUPPRESSIVE
References
DENDRITIC_CELL
CASCADE:FLT3LG
PMID:10753833
GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription
PMID:16418395
FLT3L induces PU.1 and STAT3 mRNA expression in DC progenitors and downregulates GATA1 mRNA expression.
Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- GATA1@INNATE_IMMUNE_CELL_Cytosol
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
- GATA1:SPI1@INNATE_IMMUNE_CELL_Cytosol
Participates in reactions:
As Reactant or Product:- GATA1:SPI1@INNATE_IMMUNE_CELL_Cytosol
→
degraded
- GATA1@INNATE_IMMUNE_CELL_Cytosol
+ SPI1@INNATE_IMMUNE_CELL_Cytosol
→
GATA1:SPI1@INNATE_IMMUNE_CELL_Cytosol
- rGATA1@INNATE_IMMUNE_CELL_Cytosol
→
GATA1@INNATE_IMMUNE_CELL_Cytosol
As Catalyser: