Complex IL6R:SOCS3:gp130* map
Complex composition:

  1. gp130* map
  2. IL6R map
  3. SOCS3 map

IL6R:​SOCS3:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Cytosol

Identifiers
NAME:IL6R:SOCS3:gp130*

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / IMMUNOSUPPRESSIVE_CYTOKINE_PATHWAYS  map

References
PMID:12754507, PMID:24418198
SOCS3 binds with high affinity to the phosphorylated Tyr759 (Y759)
Of gp130 to suppress IL-6 signaling in macrophages.

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. IL6R:​SOCS3:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. SOCS3@INNATE_IMMUNE_CELL_Cytosol map + IL6R:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Membrane map → map IL6R:​SOCS3:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Cytosol map
  2. IL6R:​SOCS3:​gp130*|​Y759_pho@INNATE_IMMUNE_CELL_Cytosol map → map degraded
As Catalyser: