Protein CXCL6 map

Identifiers
C-X-C motif chemokine ligand 6
HUGO:CXCL6 hgnc_id:HGNC:10643 HGNC:10643 ENTREZ:6372 UNIPROT:P80162
HUGO:CXCL6

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CYTOKINES_CHEMOKINES_PRODUCTION  map

References
PMID:24406209
CXCL6, like CXCL8, is involved in the recruitment of neutrophils.
 NEUTROPHIL  map
CASCADE:RECRUITMENT_OF_IMMUNE_CELLS
PMID:21236563
Another chemokine recently
shown to be important in the recruitment of neutrophils to melanoma
tumors is GCP-2 (CXCL6). Specific anti-CXCL6 monoclonal antibodies
not only reduced recruitment of neutrophils to tumor sites in
mice but also caused reduction in tumor growth


Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR_Membrane
  1. CXCL6@TUMOR_CELL_AS_INDUCTOR_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CXCL6@TUMOR_CELL_AS_INDUCTOR_Membrane map map RECRUITMENT_OF_IMMUNE_CELLS@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: