Protein CCR5 map

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / RECRUITMENT_OF_IMMUNE_CELLS  map

References
 DENDRITIC_CELL  map
 NATURAL_KILLER  map
CASCADE:CCR5
CASCADE:IFNAB
PMID:11698286
IFNA induces surface expression of CCR5 in Dcs. This higher expression of CCR5 was associated with a stronger chemotactic response of IFN-DCs to the ??-chemokines CCL5(RANTES), CCL3(MIP-1??), and, especially, CCL4( MIP-1??).
PMID:11790543, PMID:15356122
CCR5 as a critical NK-cell homing receptor,
CCL5 expression at the tumor site determined the effectiveness of the antitumor response, which was associated with infiltration of increased numbers of NK, CD4, and CD8 cells at the tumor site.


Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CCR5@INNATE_IMMUNE_CELL_Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CCR5@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CCR5@INNATE_IMMUNE_CELL_Cytosol map map CCR5@INNATE_IMMUNE_CELL_Membrane map
    2. CCR5@INNATE_IMMUNE_CELL_Membrane map map CCR5@INNATE_IMMUNE_CELL_Membrane map
    3. CCR5@INNATE_IMMUNE_CELL_Membrane map map RECRUITMENT_OF_IMMUNE_CELLS@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: