Protein RHEB map

Identifiers
HUGO:HREB
HUGO:RHEB
Ras homolog enriched in brain
HUGO:RHEB HGNC:10011 ENTREZ:6009 UNIPROT:Q15382
HUGO:RHEB HGNC:10011 ENTREZ:6009 UNIPROT:Q15382 GENECARDS:RHEB REACTOME:63056 KEGG:6009 ATLASONC:GC_RHEB WIKI:RHEB
Q15382

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Innate Immunity  map  / IMMUNOSTIMULATORY_CORE_PATHWAYS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:12906785 PMID:19022819 PMID:23087689
 DENDRITIC_CELL  map
 NATURAL_KILLER  map
PMID:12906785, PMID:19022819
AKT activates Rapamycin associated protein FRAP2 ( mTOR ) probably through Tuberin/GTP-binding protein Ras homolog enriched in brain ( RHEB ) pathway.
PMID:19143635
PMID:18466115

Modifications:
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. GDP:​RHEB@INNATE_IMMUNE_CELL_Cytosol map
  2. (GTP:​RHEB)|​active@INNATE_IMMUNE_CELL_Cytosol map
Participates in reactions:
As Reactant or Product:
  1. (GTP:​RHEB)|​active@INNATE_IMMUNE_CELL_Cytosol map + GDP@INNATE_IMMUNE_CELL_Cytosol map → map GDP:​RHEB@INNATE_IMMUNE_CELL_Cytosol map + GTP@INNATE_IMMUNE_CELL_Cytosol map
As Catalyser:
  1. DEPTOR:​MLST8:​ORP1L*:​PRAS40*:​RILP@INNATE_IMMUNE_CELL_Cytosol map → map (DEPTOR:​MLST8:​MTOR|​pho:​PRAS40*:​RPTOR)|​active@INNATE_IMMUNE_CELL_Cytosol map