Gene CCL5 map

Identifiers
HUGO:CCL5

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CYTOKINES_CHEMOKINES_PRODUCTION  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / RECRUITMENT_OF_IMMUNE_CELLS  map

References
CASCADE:TGFB
PMID:23034983
TGFB upregulates gene expression of CAF markers ,??FSP1 (S100A4), and??TNC. (provably via SMAD3), and gene expression of CCL5, SDF1(CXCL12), BMP4, IL6, CXCL7, IL6R, IL6ST, CXCL5
 NEUTROPHIL  map
PMID:19732719??
Inhibition of TGF-?? signaling downregulates Arginase1, CCL5 and CCL2 expression and upregulates TNF, ICAM1,CCL3 expression (mRNA) in tumor neutrophiles (TAN)

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gCCL5@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gCCL5@INNATE_IMMUNE_CELL_Cytosol map → map rCCL5@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: