Identifiers
HUGO:CCR7
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / RECRUITMENT_OF_IMMUNE_CELLS
References
DENDRITIC_CELL
CASCADE:IFNAB
CASCADE:CATENINB
PMID:17936032
Beta-catenin signaling upregulates CCR7, both at the mRNA level and on the plasma membrane.
CCR7 is a chemokine receptor important for the migration of DCs from the periphery to T cell areas of lymph node
PMID:11698286
IFNA induces mRNA expression both CCR7 and its ligand CCL19 in Dcs and induces Dcs migration