Protein ID1 map

Identifiers
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
HUGO:ID1, HGNC:5360, ENTREZ:3397 , UNIPROT:P41134
HUGO:ID1

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map

References
PMID:17490644
Snai1 and TCF3 (E47) upregulate both mRNA and protein level of ID1
This upregulation depends on SP1 or AP1 co-transcription factors
CASCADE:VEGFA
 DENDRITIC_CELL  map
PMID:16002046
Id1???/??? DCs did not respond to the VEGF stimulus because of defective Flt-1 signaling in these mutant mice. Thus, Flt-1 seems to be an important player in VEGF???DC interactions.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. ID1@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ID1@INNATE_IMMUNE_CELL_Cytosol map → map ID1@INNATE_IMMUNE_CELL_Cytosol map
    2. ID1@INNATE_IMMUNE_CELL_Cytosol map → map IMMUNE_SUPRESSION@default map
    As Catalyser: