Identifiers
HUGO:HLX
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / MIRNA_TF_IMMUNOSTIMULATORY
References
NATURAL_KILLER
PMID:12055627, PMID:14614857
T-Bet induces HLX in T cells, and probably in NK cells.
HLX activates IFNG expression.
T-bet expression was approximately 4-fold reduced in GATA-3 deficient NK cells compared to controls, while Hlx expression was about 10-fold reduced