Gene MIR15/16* map

Identifiers
HUGO:MIR15A HUGO:MIR15B HUGO:MIR16-1 HUGO:MIR16-2

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
 Innate Immunity  map  / MIRNA_TF_IMMUNOSUPPRESSIVE  map

References
 NATURAL_KILLER  map
CASCADE:KLRB1
CASCADE:IL12
CASCADE:IL15
PMID:22379033
IL-15 plus IL-12, or plate-bound anti-NK1.1, resulted in a significant reduction of miR-15b in both conditions, and a significant reduction in miR-15a and miR-16 in the 12+15 condition
miRs-15a/15b/16 were identified as abundant miRNAs in NK cells that directly target the murine IFNG 3'UTR.
PMID:22701882
IL2,IL15,IL21 upregulate MIR155, MIR15a, mir1246 in NK cells.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gMIR15/16*@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMIR15/16*@INNATE_IMMUNE_CELL_Cytosol map → map arMIR15/16*@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: