Identifiers
HUGO:CEBPB
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / SENESCENCE
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity / MIRNA_TF_IMMUNOSUPPRESSIVE
References
PMID:18555778
PMID:18555777
There is a positive feedback loop between IL6 and CEBP that help maintain the senescence state
MDSC
CASCADE:GSF3
PMID:20581311
STAT3 as an essential mediator of emergency granulopoiesis by its regulation of transcription factors that direct G-CSF-responsive myeloid progenitor expansion.
STAT3 directly controls G-CSF-dependent expression of CCAAT-enhancer-binding protein ?? (C/EBP??), a crucial factor in the emergency granulopoiesis response.