Identifiers
HUGO:S100A8
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / RECRUITMENT_OF_IMMUNE_CELLS
References
MDSC
MACROPHAGE
PMID:18809714
STAT3 depletion resulted in the down-regulation of S100A8 and S100A9 gene expression
The promoter regions of S100A8 and S100A9 contain several potential STAT3 binding sites (TTCCC G/A G/T AA). In chromatin immunoprecipitation assays of 32D myeloid cells, STAT3 interacted with the promoter regions of both S100A8 and S100A9.