Identifiers
HUGO:IL2RB
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS
References
NATURAL_KILLER
DENDRITIC_CELL
PMID:18003603
RUNX proteins down-regulates IFNG expression in NK cells and upregulates expression of CD122 (IL-2/IL-15 common receptor beta subunit) via direct binding to its promoter.
PMID:22608498
ETS1 binds directly to the Tbx21 and IL2RB (CD122) genes and induces its expression in NK cells.