Identifiers
HUGO:DUSP1
dual specificity phosphatase 1
PTPN10
HUGO:DUSP1 HGNC:3064 ENTREZ:1843 UNIPROT:P28562
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
Innate Immunity / IMMUNOSUPPPRESSIVE_CORE_PATHWAYS
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / MAPK
References
PMID:23124025, PMID:16184516
IL13 induces DUSP1 expression via TYK2 and probably STAT6
In silico??analysis identified a STAT6 binding site at position +99 (relative to the transcriptional start site) of the mouse DUSP1 promoter.??
PMID:16184516
IL-10 induces the expression of DUSP1, which negatively regulates p38 phosphorylation and thus limits IL-10 production
References
in_re1117( Innate Immunity ):
PMID:23124025
IL13 induces DUSP1 expression via TYK2 and probably STAT6