Identifiers
HUGO:IRAK3
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / IMMUNOSTIMULATORY_CORE_PATHWAYS
References
PMID:12150927
IRAK3 (IRAK-M) is a negative regulator of Toll-like receptor signaling
in macrophages. It prevented dissociation of IRAK and IRAK-4 from MyD88 and formation of IRAK-TRAF6 complexes.
PMID:21278795
TGFB-induced IRAK3 (IRAK-M) expression in tumor-associated macrophages
and inhibit TLR-dependent signaling
References
in_re731( Innate Immunity ):
PMID:21278795
TGFB-induced IRAK3 (IRAK-M) expression in tumor-associated macrophages
and inhibit TLR-dependent signaling