Gene MAOA map

Identifiers
HUGO:MAOA

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / NO_ROS_PRODUCTION  map

References
PMID:23124025
IL13 induces expression of MAOA and ALOX15 via JAK1, TYK2, STAT1 STAT3 and STAT6
IL4 induces expression of MAOA and ALOX15 via JAK1, STAT3 and STAT6.
PMID:22067385
c-MYC expression is assosiated with M2 type of macrophages.
IL4 induces MYC expression in macrophages. MYC directly regulates some genes associated with alternative activation, including ARole of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology MAOA, PPARG, SCARB1, ALOX15, and MRC1, whereas others, including CD209, are indirectly regulated by c-MYC. c-MYC up-regulates the IL-4 signaling mediators signal transducer and activator of transcription-6 and peroxisome proliferator-activated receptor??, is also expressed in tumor-associated macrophages, and its inhibition blocks the expression of protumoral genes including VEGF, MMP9, HIF-1A, and TGFB.

gMAOA@INNATE_IMMUNE_CELL_Cytosol

References
in_re1100( Innate Immunity  map ):
PMID:23124025
IL13 induces expression of MAOA and ALOX15 via JAK1, TYK2, STAT1 STAT3 and STAT6
IL4 induces expression of MAOA and ALOX15 via JAK1, STAT3 and STAT6.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. gMAOA@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMAOA@INNATE_IMMUNE_CELL_Cytosol map → map rMAOA@INNATE_IMMUNE_CELL_Cytosol map
    As Catalyser: