Identifiers
HUGO:TNFSF9
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Adaptive Immune Response / ACTIVATING_CHECKPOINTS
References
PMID:8992967 PMID:16288496 PMID:9206996
DENDRITIC_CELL
NEUTROPHIL
PMID:8992967, PMID:16288496
TNFSF9 (CD137L, 4-1BBL) is expressed in DCs and induces T-cell activation adn inhibits tumor growth.
PMID:25384214
TANs enhance T cell proliferation by direct cell-cell signaling, likely due to the OX40L/OX40 and 4-1BBL/4-1BB pathways.