Protein CD70 map

Identifiers
HUGO:CD70

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / ACTIVATING_CHECKPOINTS  map

References
PMID:19062317 PMID:17237405
 DENDRITIC_CELL  map
CD70 is a costimulatory ligand acquired upon DC maturation. It stimulates T-cells and provides tumor regression.
PMID:17237405
Surface expression of CD70 in DC is TLR and CD40 dependent.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. CD70@INNATE_IMMUNE_CELL_Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD70@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CD70@INNATE_IMMUNE_CELL_Membrane map → map Immune_checkpoints_T_cells_Activators@default map
    2. CD70@INNATE_IMMUNE_CELL_Cytosol map → map CD70@INNATE_IMMUNE_CELL_Membrane map
    As Catalyser: