Identifiers
HUGO:CXCL16
Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
Innate Immunity / RECRUITMENT_OF_IMMUNE_CELLS
References
MACROPHAGE
DENDRITIC_CELL
PMID:11017100
CXCL16 is produced by DC and regulates Tcell and NKT migration.
PMID:16597464
IRF-8 and IRF-1 are the target genes in activated macrophages.
The expression levels of CXCL16, H28, IL-17R, LIF, MAP4K4, MMP9, MYC, PCDH7, PML, and SOCS7 were signi???cantly increased in macrophages
extracted form WT mice (black columns) following activation
for 4 h with IFNG and LPS. However, no changes in the expression of these genes were observed in cells extracted from IRF-8,
as well as from IRF-1 null mice.