Reaction transcription in_re721
gTNFR1*@INNATE_IMMUNE_CELL_Cytosol
→ rTNFR1*@INNATE_IMMUNE_CELL_Cytosol
Reaction regulators:
- Inhibition
- SOCS1@INNATE_IMMUNE_CELL_Cytosol
- Unknown_catalysis
- STAT1|pho|active@INNATE_IMMUNE_CELL_Cytosol
References
PMID:12193701
INFG upregulates TNFR1 expression, probably via JAK/STAT1 pathway
because this expression is inhibited in presense of SOCS1.